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Vorinostat (SAHA)

Part Number:EI-HDC-002
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Vorinostat



Suberoylanilide-hydroxamic acid;SAHA

Vorinostat is a potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. Synergizes with kinase inhibitors to kill CNS tumor cells. Prevents diabetes in a mouse model by immunoregulation and b-cell protection. Cell permeable.

Physical Properties: White powder

MW=264.3 C14H20N2O3

Analysis: >98%; NMR (Conforms)

Solubilization: May be dissolved in DMSO (50 mg/ml); or Ethanol (2 mg/ml)

Storage: Store desiccated as supplied at ambient temperature for up to 5 years. Store solutions at -20°C for up to 1 month.


Amount: 10mg