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Trichostatin A

Part Number:EI-HDC-005
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Trichostatin A

(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; TSA

Trichostatin A is a potent and selective histone deacetylase (HDAC) inhibitor (Ki=3.4 nM).Induces reversion of ras-transformed cells to normal morphology. Induces dedifferentiation ofprimordial germ cells into embryonic germ cells. Cell permeable. Active in vivo.

Physical Properties: Beige powder; MP=150-151°C
MW=302.4 C17H22N2O3

Analysis: >99% (HPLC); NMR conforms

Solubilization: May be dissolved in DMSO (15 mg/ml); or ethanol (3 mg/ml)

Storage: Store as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.

Amount: 1 mg