TM-2-51
Highly potent and isozyme selective activator of recombinant HDAC8. Increases the activity of HDAC8 by a factor of 12 at 10 µM. No activation of other HDACs is observed. Rescues the activity of catalytically compromised HDAC8 mutants in vitro.
Amount: 10mg
Physical Properties: Beige powderMW=256.3 C14H12N2OS
Analysis: >98% (TLC); NMR (Conforms)
Solubilization: May be dissolved in DMSO (50 mg/ml); or ethanol (8 mg/ml)
Storage: Store desiccated as supplied at -20°C for up to 2 years. Store solutions at-20°C for up to 3 months.
