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RVX-208

Part Number:EI-BRD-001
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RVX-208



RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 µM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis.

Amount: 5mg

Physical Properties: White powder

MW=370.4 C20H22N2O5

Analysis: >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (75 mg/ml); or ethanol (4 mg/ml)

Storage: Store desiccated as supplied at -20°C for up to 2 years. Store solutions at-20°C for up to 1 month.