CPTH2
Cyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl]hydrazone, CPTH2 is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.800 mM). In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. In vivo it decreased acetylation of bulk histone H3 at the H3-AcK14 site.
Amount: 5mg
Physical Properties: White powder
MW=291.8 C14H14ClN3S
Analysis: >98% (TLC); NMR (Conforms)
Solubilization: May be dissolved in DMSO (>25 mg/ml)
Storage: Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to one month.
