BML-278
N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
BML-278 is a structurally novel activator of SIRT1 (EC150=1 mM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 mM respectively). Cell permeable.
Physical Properties: off white powder; MP=141-143°CMW=391.5 C24H25NO4
Analysis: >98% (TLC); NMR conforms
Solubilization: May be dissolved in DMSO (5 mg/ml)
Storage: Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20°C for up to 3 months.
Amount: 5mg 
