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Your Price:$60.50
In Stock.
Part Number:EI-DNA-005

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1H-?b-?D-?ribofuranosyl-?2-?pyrimidinone; NSC 309132


DNA methyltransferase inhibitor which binds covalently to methyltransferases. Re-activates silenced E-cadherin expression in EBV-harboring Burkitt’s lymphoma Akata cells. Delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer. Potentiates differentiation of mesenchymal stem cells into cardiomyocytes. Inhibits cytidine deaminase (Ki ~ 2 µM). Active in vivo.

Physical Properties:  White powder

MW=228.2          C9H12N2O5

Analysis=98% (HPLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (20 mg/ml); or water (20 mg/ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month.

Amount: 5mg

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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