Vorinostat is a potent and selective histone deacetylase inhibitor.
Induces apoptosis in a variety of tumor cell lines. Synergizes with
kinase inhibitors to kill CNS tumor cells. Prevents diabetes in a
mouse model by immunoregulation and b-cell
protection. Cell permeable.
Physical Properties: White powder
Analysis: >98%; NMR (Conforms)
Solubilization: May be dissolved in DMSO (50 mg/ml); or Ethanol (2 mg/ml)
Storage: Store desiccated as
supplied at ambient temperature for up to 5 years.
Store solutions at -20°C for up to 1 month.