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UHRF1-[SRA] (His)

Your Price:$303.00
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Part Number:RD-11-235

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DESCRIPTION: Human recombinant UHRF1 SRA domain expressed as an N-terminal His-fusion protein in E. coli. A tumor promoter overexpressed in a wide variety of cancers, the epigenetic regulator UHRF1 is a multidomain protein that co-localizes with DNMT1 and functions in the maintenance of DNA methylation patterns. Its SRA domain is an epigenetic reader that specifically binds 5-methylcytosine at hemimethylated CpG sites.             

ACCESSION #: NM_001048201

Uniprot Link


TAG(S): N-terminal His tag

MW: 25.4 kDa


SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v)

STORAGE: -70°C. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<5 µl) or storage of diluted protein is not recommended.

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With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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