arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 µM.
Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits
growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks
androgen-induced gene expression in LNCaP cells.
Physical Properties: Brown
Analysis: >98% (TLC); NMR (Conforms)
be dissolved in DMSO (50 mg/ml); or ethanol (nil)
desiccated as supplied at -20°C for up to 2 years. Store solutions at 20°C for
up to 1 month.
Amount: 50 mg