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Your Price:$104.50
In Stock.
Part Number:EI-SRT-008

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Sirtinol is a selective sirtuin inhibitor which does not effect HDAC1, IC50 = 131, 38 and 68 mM for SIRT1, SIRT2 and Sir2P respectively. Induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells. Suppresses survivin expression which correlates with decreased viability in HT29 colon cancer cells. Displays pro-inflammatory effects in adipocytes.

Physical Properties: Yellow powder

MW=394.5          C26H22N2O2

Analysis: >98% (TLC); NMR conforms

Solubilization: May be dissolved in DMSO (35 mg/ml) or ethanol (10 mg /ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at         -20°C for up to 1 month.

Amount: 5mg

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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