Human recombinant SMARCA2a bromodomain. The core catalytic subunit for a subset of the BAF type SWI/SNF ATP-dependent chromatin remodeling complexes, SMARCA2 may be a promising target for therapy in cancers in which the alternative catalytic subunit, SMARCA4/BRG1, is mutated, rendering the cells dependent on SMARCA2 function
ACCESSION #: NM_003070
Uniprot Link
INCLUDES AMINO ACIDS: 1367-1511
TAG(S): N-terminal GST tag
MW: 43.9 kDa
EXPRESSION SYSTEM: E.coli
SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris/HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v)
STORAGE: -70°C. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<5 µl) or storage of diluted protein is not recommended.
