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SGC707

Part Number:EI-HMT-006
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SGC707

1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea

Potent and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3)1. IC50 = 31 nMand selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.

Physical Properties: Beige crystalline powder; MP=233-235°C

MW= 298.3 C16H18N4O2

Analysis: >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (35 mg/ml)

Storage: Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.

Amount: 5 mg