Potent and selective allosteric inhibitor of protein
arginine methyltransferase 3 (PRMT3)1. IC50 = 31 nM and selective against 31 other
methyltransferases. An extremely useful probe for investigating the role of
PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.
Physical Properties: Beige crystalline
Analysis: >98% (TLC);
Solubilization: May be dissolved
in DMSO (35 mg/ml)
Storage: Store desiccated as
supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.
Amount: 5 mg