Human recombinant SETD2 expressed as an N-terminal GST-fusion protein in E. coli. While not required to product H3K36me1/2, SETD2 is the enzyme largely responsible for trimethylation at H3K36 (H3K36me3) in mouse fibroblasts, a mark associated with transcription elongation.
ACCESSION #: NM_030648
Uniprot Link
INCLUDES AMINO ACIDS: 1433-1711
TAG(S): N-terminal GST-tag
MW: 58.7 kDa
EXPRESSION SYSTEM: E. coli
SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris/HCl pH 7.5, 150 mM NaCl, 1 mM TCEP, 10% glycerol (v/v).
STORAGE: -80°C, aliquot and snap-freeze after first use.
