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RG-108

Part Number:EI-DNA-003
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RG-108


N-Phthalyl-L-tryptophan; or (S)-2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid


RG-108 is a non-nucleoside DNA methyltransferase inhibitor. IC50=115 nM1 Inhibits DNA methylation in human tumor cell lines without toxicity2. Enhances the reversion of neural progenitor cells to the pluripotent state3.

Physical Properties: Tan powder; MP=104°C

MW=334.3 C19H14N2O4

Analysis: >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (100 mg/ml); or ethanol (100 mg/ml)

Storage: Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20°C for up to 1 month.

Amount: 5mg