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NSD2 (His) Methyltransferase

Your Price:$495.00
In Stock.
Part Number:HMT-21-138

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NSD2 (His) is a SET-domain lysine methyltransferase that exerts regulatory effects primarily through methylation of H3K36, a mark associated with gene activation, NSD2 may also act as an H4K20 methyltransferase as part of a DNA damage response.  Notable for its role in the genesis of t(4; 14) translocation-positive multiple myelomas, NSD2 is also overexpressed in a wide range of human cancers and is considered a promising target for the development of anti-cancer therapies.  

ACCESSION #: NM_001042424

Uniprot Link


TAG(S): N-terminal His-tag

MW: 155.5 kDa

EXPRESSION SYSTEM: Insect cell/Baculovirus

SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris/HCl pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v).

STORAGE: -80°C, aliquot and snap-freeze after first use.

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Substantial Discounts Available on Bulk Quantities

We also offer assay services for NSD2 (His).                  

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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