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ML-324

Part Number:EI-DEM-005
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ML-324

N-(3-(dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide

ML324 inhibits JMJD2 histone demethylases. (JMJD2 IC50=920 nM) Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 mM) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons. Cell permeable.

Physical Properties: Light brown-colored powder

MW=349.4 C21H23N3O2

Analysis: >98% (TLC); NMR (Conforms)

Solubilization: Soluble in DMSO (20 mg/ml, warm); or ethanol (6 mg/ml, warm)

Storage: Store desiccated as supplied at -20°C for up to 1 year. Store solutions at -20°C for up to 1 month.

Amount: 5mg