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Your Price:$84.70
In Stock.
Part Number:EI-DEM-003

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8-Hydroxy-5-quinolinecarboxylic acid; (5-Carboxy-8HQ)

IOX1 inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 mM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively1. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling1. Cell permeable

Physical Properties:  Yellow powder

MW=189.2          C10H7NO3  

Analysis:  >98% (HPLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (20 mg/ml)

Storage:  Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20°C for up to 3 months.

Amount: 5 mg

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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