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Histone H2A

Your Price:$55.00
In Stock.
Part Number:HMT-11-146

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DESCRIPTION:
Full-length, untagged human recombinant histone H2A expressed in E. coli. One of the four, core nucleosomal histones, H2A forms dimers with histone H2B, two of which associate with the H3-H4 tetratmer (H3-H4)2, forming the core octamer of the nucleosome. Histone H2A is subject to multiple regulatory post-translational modifications including ubiquitination, phosphorylation, acetylation, arginine and lysine methylation and crotonylation. RBC’s Histone useful for the assay of various protein arginine methyltransferases (e.g. PRMT1, PRMT5) either by radiolabeling with [3H]-S-adenosylmethionine (e.g. gel electrophoresis/autoradiography or filterplate/scintillation counting) or by non-radiolabeled methods (e.g. coupled assays detecting the product S-adenosylhomocysteine). 

ACCESSION #: NM_021052

Uniprot Link

INCLUDES AMINO ACIDS: 1-130

TAG(S): None

MW: 14.1 kDa

EXPRESSION SYSTEM: E. coli

SUPPLIED AS: Solution of purified recombinant protein in 50 mM HEPES/NaOH pH 7.1, 10 mM KCl, 1 mM DTT, 1 mM EDTA, 10% glycerol (v/v).

STORAGE: -80°C, aliquot and snap-freeze after first use.

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With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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