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GLP Methyltransferase Protein

Your Price:$329.00
In Stock.
Part Number:HMT-11-103

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GLP, in complex with the highly homologous G9a, is the major histone H3 lysine-9 (H3K9) methyltransferase for euchromatin and can also dimethylate p53K373, a modification correlating with levels of inactive p53. This latter result, along with the fact that GLP and G9a are overexpressed in a variety of human cancers suggests G9a/GLP inhibition as a potential anti-cancer therapy, especially for tumors expressing wild-type p53.

ACCESSION #: NM_024757

Uniprot Link

INCLUDES AMINO ACIDS: 894-1298 (C-term.)

TAG(S): N-terminal GST-tag

MW: 80.0 kDa


SUPPLIED AS: Solution of purified recombinant protein in 25.4 mM Na2HPO4/NaH2PO4, pH 7.4, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 30% (w/v) glycerol.

STORAGE: -80°C, aliquot and snap-freeze after first use. first use.

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We also offer assay services for GLP.

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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