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EP300 (GST)

Your Price:$320.00
In Stock.
Part Number:RD-11-263

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**Please note that shipping and dry ice charges will be included in your final invoice.**

Human recombinant EP300 bromodomain. EP300 and the closely related CREBBP (CBP) are major regulators of gene transcription (co-activators) and function as lysine acetyltransferases for histones (i.e. HATs) and for numerous other proteins (e.g. p53). Aside from the acetyllysine-binding bromodomain and the catalytic HAT domain, native EP300 comprises multiple protein-protein interaction domains (3 Cys-His-rich (CH) domains, KIX domain, steroid receptor co-activator interaction domain (SID)) and also has E3 and E4 ubiquitin ligase activities.

ACCESSION #: NM_001429

Uniprot Link


TAG(S): N-terminal GST

MW: 41.4 kDa


SUPPLIED AS: Solution of purified recombinant protein in 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10% glycerol (v/v)

STORAGE: -70°C. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<5 µl) or storage of diluted protein is not recommended.

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Substantial Discounts Available on Bulk Quantities            

We also offer assay services for EP300 (GST).

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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