DNA Repair Proteins

RBC's DNA Demethylation and Repair offering currently includes the APE1 protein. APE1 is involved in numerous cellular processes involving DNA demethylation and repair classifying it as an epigenetic target as it plays a role in the epigenetic regulation of gene expression. APE1 is responsible for the incision of DNA basic sites during base excision repair, and also stimulates the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. Reaction Biology offers His- and GST- tagged APE1 proteins.
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