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DNA Demethylation & Repair

RBC's DNA Demethylation and Repair offering currently includes the APE1 protein. APE1 is involved in numerous cellular processes involving DNA demethylation and repair classifying it as an epigenetic target as it plays a role in the epigenetic regulation of gene expression. APE1 is responsible for the incision of DNA basic sites during base excision repair, and also stimulates the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. Reaction Biology offers His- and GST- tagged APE1 proteins.
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With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

Reaction Biology Corp. 1 Great Valley Parkway, Suite 2 Malvern, PA 19355 1-877-347-2368 or 610-722-0247
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