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DMOG

Your Price:$55.00
In Stock.
Part Number:EI-DEM-004

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DMOG


N-(2-Methoxy-2-oxoacetyl)glycine methyl ester; Dimethyloxalylglycine


DMOG inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1a and inhibiting JMJD2A (IC50 = 2.5 mM). Displays neuroprotective effects. Inhibits neuronal cell death caused by neurotrophin deprivation. Prevents activation of the ATR/CHK1/p53 pathway and suppresses apoptosis induced by DNA damage.


Physical Properties:  White to off-white solid; MP=46-48°C

MW=175.1       C6H9NO5

Analysis:  >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (30 mg/ml), ethanol (25 mg/ml), or water (30 mg/ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at   -20°C for up to 1 month.  

Amount:10  mg























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