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CPTH2

Your Price:$81.40
In Stock.
Part Number:EI-HAT-003

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CPTH2
 


Cyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl]hydrazone, CPTH2 is a selective inhibitor of the histone acetyltransferase Gcn5P both in vitro and in vivo (IC50 = 0.800 mM).  In vitro, the HAT inhibitory activity of CPTH2 was caused via bridge-interaction with histone H3. In vivo it decreased acetylation of bulk histone H3 at the H3-AcK14 site.

Amount: 5mg

Physical Properties:  White powder 

MW=291.8          C14H14ClN3S

Analysis:  >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (>25 mg/ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to one month.











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