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Your Price:$98.00
In Stock.
Part Number:EI-HAT-001

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4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid

    C-646 is a potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM )1. Induces apoptosis in prostate cancer cells2. Enhances fear extinction memory and synaptic plasticity in mice3. Promotes tau deacetylation reducing levels of pathogenic p-tau4. Cell permeable.          

Physical Properties:  Orange powder

MW=445.4          C24H19N3O6

Analysis: >98% (TLC); NMR (conforms)

Solubilization: May be dissolved in DMSO (10 mg/ml)

Storage:  Store desiccated as supplied at 4°C for up to 2 years. Store solutions at -20°C for up to 2 months.

Amount: 5 mg

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