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BML-278

Part Number:EI-SRT-003
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BML-278


N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine

BML-278 is a structurally novel activator of SIRT1 (EC150=1 mM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50 mM respectively). Cell permeable.

Physical Properties: off white powder; MP=141-143°C

MW=391.5 C24H25NO4

Analysis: >98% (TLC); NMR conforms

Solubilization: May be dissolved in DMSO (5 mg/ml)

Storage: Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20°C for up to 3 months.


Amount: 5mg