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Your Price:$75.00
In Stock.
Part Number:EI-HDC-006

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Apicidin is a cyclopeptide inhibitor of histone deacetylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1).  Decreases HIF1a protein levels and transcriptional activity in human and mouse tumor cell lines.  Cell permeable.

Physical Properties:  white powder

MW=623.8          C34H49N5O6

Analysis:  =98% (HPLC); NMR (Conforms)

Solubilization: Soluble in DMSO (10 mg/ml); or ethanol (1 mg/ml)

Storage:  Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Amount: 1mg

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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