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Your Price:$99.00
In Stock.
Part Number:EI-DNA-004

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5-Fluoro-2’-deoxycytidine; FCDR; FdCyd; NSC-48006; Ro 5-1090

2'-Deoxy-5-Fluorocytidine  DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5’-Azacytidine and decitabine, 2’-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.

Physical Properties:  White solid; MP = 196oC

MW=245.2        C9H12FN3O4

Analysis:  >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (20 mg/ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at            -20°C for up to 1 month.  

Amount: 50mg

With the largest functional kinase activity assay panel in the industry, RBC provides kinase, epigenetic, and other profiling services to over 590 companies worldwide. RBC specializes in custom assay conditions, high quality reproducible data, and outstanding service.

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