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5-Fluoro-2'-deoxycytidine

Your Price:$99.00
In Stock.
Part Number:EI-DNA-004

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2’-Deoxy-5-fluorocytidine                   



5-Fluoro-2’-deoxycytidine; FCDR; FdCyd; NSC-48006; Ro 5-1090



2'-Deoxy-5-Fluorocytidine  DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5’-Azacytidine and decitabine, 2’-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.

Physical Properties:  White solid; MP = 196oC

MW=245.2        C9H12FN3O4

Analysis:  >98% (TLC); NMR (Conforms)

Solubilization: May be dissolved in DMSO (20 mg/ml)

Storage:  Store desiccated as supplied at -20°C for up to 2 years. Store solutions at            -20°C for up to 1 month.  


Amount: 50mg











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